By 2014, ZIKV had spread to other Pacific islands: New Caledonia, the Cook Islands, and Easter Island. In addition, in 2013, the virus appeared in French Polynesia. In 2007, ZIKV emerged in the Yap Islands in the Federated States of Micronesia and also in the African country of Gabon. It was discovered in 1947 in the Zika Forest, in Uganda, and remained confined to some areas of Africa and Asia. ZIKV is a positively enveloped RNA virus member of the Flaviviridae family, genus Flavivirus ( 1, 7). Transmission can occur sexually ( 5), through blood transfusion and saliva, and from mother to child during pregnancy, birth, and breast-feeding ( 6). Aedes mosquitoes are considered the only competent vectors for ZIKV transmission ( 3, 4). There was a second isolation from Aedes africanus (Theobald) in 1948 in an attempt to isolate yellow fever virus from mosquitoes in the Zika Forest of Uganda ( 2). The virus was initially isolated in a rhesus monkey in 1947. Zika virus (ZIKV) is known to be transmitted among humans mainly through bites of Aedes aegypti (Linnaeus) and Aedes albopictus (Skuse) mosquitoes ( 1).
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